The film follows Nello, the recently hired director of a newly developed work cooperative of former mental patients. After the closure of state psychiatric hospitals and asylums in Italy under the Basaglia Law many former patients were left with few resources and little hope of reintegrating into society.

Policewoman Anna Mari is forced to play a dangerous game with the title serial killer. If she loses, she witnesses the maniac's tortured victims having their throats cut in explicit close-up detail via webcam.

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