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Lugano, Switzerland. Titta Di Girolamo is a discreet and sullen man who has been living for almost a decade in a modest hotel room, a prisoner of an atrocious routine, apparently without purpose.
In 18th-century Sicily, deaf-mute highborn Marianna Ucrìa is forced to marry at age 13, bearing three children before even turning 16, when she finally gives birth to a boy.
At the beginning of the 20th century, a junior resident takes an interest in a newly-arrived patient, a young Italian woman who has mysteriously developed schizophrenia.
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