A fanatical animal rights activist releases giant pythons into the Everglades, believing the wild animals should be set free. When they start decimating the native animal population, an over-zealous park ranger feeds experimental steroids to wild alligators so they can fight back.

Jack Shepard is an out-of-shape auto shop owner, far removed from the man who once protected the world's freedom. Reluctantly called back into action by the government, Jack is tasked with turning a ragtag group of kids with special powers into a new generation of superheroes to save the world from certain destruction.

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