Three college students, Phil, Ed, and Henry take a road trip into Mexico for a week of drinking and carefree fun only to have Phil find himself a captive of a group of satanic Mexican drug smugglers who kill tourists and whom are looking for a group of new ones to prepare for a sacrifice.

A scientist, Dr Holander, takes his niece Miranda to Mexico in an attempt to reverse the effects of the alien DNA he used to create her.

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