When a strange signal pulsates through all cell phone networks worldwide, it starts a murderous epidemic of epic proportions when users become bloodthirsty creatures, and a group of people in New England are among the survivors to deal with the ensuing chaos after.

When athletic teen Mari Collingwood opts to hang out with her friend Paige in town rather than spend an evening in with her parents vacationing at the family's remote lake house, it marks the beginning of a night no one is going to forget.

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