When Alita awakens with no memory of who she is in a future world she does not recognize, she is taken in by Ido, a compassionate doctor who realizes that somewhere in this abandoned cyborg shell is the heart and soul of a young woman with an extraordinary past.

Some of Sin City's most hard-boiled citizens cross paths with a few of its more reviled inhabitants.

Ex-Federale agent Machete is recruited by the President of the United States for a mission which would be impossible for any mortal man – he must take down a madman revolutionary and an eccentric billionaire arms dealer who has hatched a plan to spread war and anarchy across the planet.

After being set-up and betrayed by the man who hired him to assassinate a Texas Senator, an ex-Federale launches a brutal rampage of revenge against his former boss.

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