Locals in an Italian village believe evil has taken over the estate of a recently deceased pianist where murder has taken place.

In 19th Century Paris, a maniac abducts young women and injects them with ape blood in an attempt to prove ape-human kinship but constantly meets failure as the abducted women die.

Tampering with life and death, Henry Frankenstein pieces together salvaged body parts to bring a human monster to life; the mad scientist's dreams are shattered by his creation's violent rage as the monster awakens to a world in which he is unwelcome.

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