A giant alligator goes head to head with a giant Anaconda. The town sheriff must find a way to destroy the two monsters before they kill the whole town.
On the trail of her missing sister, Charlotte enlists the help of Wayne, an ex-Marine and alcoholic, to infiltrate the Church of One Accord - a community of snake-handlers who risk their lives seeking salvation in the Holy Ghost.
A fanatical animal rights activist releases giant pythons into the Everglades, believing the wild animals should be set free. When they start decimating the native animal population, an over-zealous park ranger feeds experimental steroids to wild alligators so they can fight back.
After being diagnosed with brain cancer, a desperate American man kidnaps the reptilian lover of the snake goddess in hopes of gaining immortality.
A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.
A set of vipers has been taken by scientists to mutate them to make a cure for cancer. As their experiment goes awry, the vipers escape into the woods - they're not only biting people, they're actually killing people, in a little town.
Cancer-terminal tycoon Peter Murdoch's secret Wexel Hall Pharmaceuticals lab has developed a blood orchid extract cure. To examine why it works optimally in snakes, they also bread a super-anaconda strain.
Duff Daniels (John T. Woods), the younger, stupider brother of Les (Michael Shanks), can't help himself from stealing a rare snake that's been kept in a jar by a Native American snake dealer (Ben Cardinal), and which has to follow some rules: don't let it out of the jar, then don't let it eat anything anything living, and never fear the heart of the snake.
FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial.
Under a powerful Mayan curse, snakes are hatched inside a young woman, slowly devouring her from within. Her only chance for survival is a powerful shaman who lives across the border.
A group of teenagers journeys to a remote forest in search of a friend who's been reported as lost after his trip to the forest.
A group of teenagers fear for their lives in the swamps of Louisiana, chased by Mr. Jangles, a man possessed by 13 evil souls, and now relentless in his pursuit of new victims.
A team of environmentalists, including a reporter, her camera man, and an environmentalist's famous girlfriend charter a boat and with the captain, sail to a military island.
An object is found that points to the secret of eternal youth so a research team is sent to find the fountain only to find it is protected by a giant snake
After an overly ambitious businessman transports an 80-foot python to the United States, the beast escapes and starts to leave behind a trail of human victims.
The blood orchid - a rare flower that could hold the secret of eternal life and be worth a fortune to the company that finds it first.
A man, his business partner, and his wife are enlisted to transport an unknown object from a Russian military base, only to discover that the object is a giant, genetically-altered python.
Paleontologist Robert Trenton is called to Northeastern Antarctica near the Indian Ocean to help the FBI build an underground maximum-security military base and prison for the world's most dangerous criminals and terrorists, which is dubbed "New Alcatrax" by the staff.
Mutant snakes survived a terrorist attack on a government laboratory, and they now threaten the town of Santa Mira Springs, California.
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